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Medical news today AIDS / HIV: remission of an HIV-positive affected person without a bone marrow transplant – FRANCE 24

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medical news today Un homme porteur du virus du sida en rémission depuis plus d'un an pourrait être le premier patient adulte à guérir de la maladie sans avoir eu besoin d'une greffe de moelle osseuse

A man carrying the virus AIDS in remission for more than a year could be the first adult affected person to recover from the disease without the need for a bone marrow transplant Romeo GACAD AFP / Archives

Paris (AFP)

A man carrying the AIDS virus in remission for more than a year could be the first affected adult person to recover from the disease without having ecu in need of a bone marrow transplant: a potential breakthrough announced by researchers on Tuesday.

This case was presented at the 23rd International AIDS Conference, for the first time fully held online from July 6 to 10, due to Covid-19.

HIV affects people tens of hundreds of thousands of people around the world. Although the disease is no longer synonymous with certain death as it once did, HIV-positive sufferers must have lifelong treatment.

In recent years, two men – dubbed “Berlin” and “London” sufferers – appear to have been cured after undergoing a bone marrow transplant high risk to treat most cancers.

An international team of researchers believe they have a third affected person who no longer shows signs of infection after following a different treatment.

The affected person, a 34-year-old Brazilian whose name has not been released, was diagnosed with HIV in 2012. As part of the study, he received several powerful antiviral drugs, including maraviroc (trade name Celsentri) and dolutegravir (Tivicay), to see if they could help him get rid of the virus.

After more than 57 weeks without anti-HIV treatment, this affected person remains negative at the anti-HIV antibody check.

Ricardo Diaz, expert in infectious diseases at the University of Sao Paulo, believes that the affected person can be considered free from the disease. “The important thing for me is to have an affected person who was on treatment and who now controls the virus without treatment,” he told AFP.

“We are unable to detect the virus and it loses the specific response virus – if you don’t have an antibody, you don’t have an antigen “(no virus, editor’s note), he adds.

According to the UN, 1.7 million people contracted HIV a year last and more than 40 hundreds of thousands of people currently live with.

According to Dr. Diaz, the method of treatment of his team, which requires additional research, is a more ethical path for seriously ill people living with HIV than that of bone marrow transplant bone.

For Sharon Lewin, director of the Doherty Institute for Infection and Immunity in Melbourne, the con Ricardo Diaz’s clusions are “very interesting”, even if she notices limits to the study. “This very challenging data needs to be further analyzed,” she said.

Several prolonged remissions have moreover, they have been reported worldwide without a cure being able to be affirmed.

© 2020 AFP

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